Nisbet House is a substantial baronial style mansion in Nisbet, Berwickshire. It was built in about 1630 by Sir Alexander Nisbet. Architectural evidence suggests that the building incorporates, at its eastern end, the square pele tower that was the former Nisbet Castle.
Sir Alexander Nisbet overextended his finances in supporting Charles I in the Civil War, and was forced to sell the property to John Ker in 1652. A square tower in the classical style of William Adam was added to the west end in 1774.
The house remained with Ker descendants (latterly in the person of Lord Sinclair) until the 1950s, when the estate were sold to Lord Brockett. After partial modernisation, the house was sold again in the mid-1960s to a local farmer, and remained unoccupied until its recent and comprehensive restoration as a private residence.