One of the first in Scotland recorded to bear the name was a Sir John M’Kirel who fought well at the 1388 battle of Otterburn.
During the reign of William the Lion (1165-1214) a Recherus Mecmaccharil was witness to confirmation by Dunekan, Earl of Karic of a charter by Roger de Scallebroc of the lands in Carrik. During the same period, a charter of lands in Roxburgh to Melrose Abbey by Richard de Moreville, was witnessed by Radulfus Makerel.
In 1376, a Gilbert M’Corrill was a tenant under Douglas in the barony of Buittle, whilst another Gilbert Makcorle, in 1481, was tenant of the Grange of Ballyndune super Cree. A further Gilbert M’Carole was a witness in Dumfries in 1534, and he appears again seven years later in 1541 as M’Carrule.
A William McKeirell was the sheriff-clerk of Ayr in 1595, and appears as McCarrell and McKerrell in following years.